This guide will take approximately 5 minutes to complete.
The purpose of this guide is to walk through how to find articles to answer questions about the prevalence of a biomarker in a disease population of interest.
Step 0: Login
Navigate to https://med.causaly.com
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Option 1: Search for prevalence data of target X mutations in disease X
To find prevalence data for mutations of a specific gene in a disease of interest, use Causaly Discover in the Causaly home page (Figure 1).
Figure 1. Causaly Discover on the Causaly homepage
Begin your search by typing your question into the Causaly Discover search bar in natural language (Figure 2). “What is the frequency of KRAS gene mutations in patients with NSCLC?” will be used as an example (link).
Figure 2: Directly ask a question in natural language in the Causaly Discover search bar
Click "Search" or hit Enter on your keyboard to run the search, which will direct you to the Causaly Discover results page.
Causaly Discover offers an AI-generated summary, complete with in-line citations for transparency into the results, based on the top 20 articles. You can scroll down to view all the documents retrieved in response to your search query.
TIP!
- To focus on a specific geographic area, age group or any other criteria to refine your cohort, ask a follow-up question on the Copilot sidebar (Figure 3).
Figure 3: Type your follow up question in natural language in the Copilot side bar on the right - To refine the results based on your research objectives and/or quality standards, use the filters panel. Once you apply filters, the AI-generated summary will be automatically updated to reflect your filter selections.
Option 2: Search for the incidence of disease Y in patients with target X mutations background
To find quantitative data regarding the incidence of a condition in patients with specific genetic mutations, use Causaly Discover in the Causaly home page.
Begin your search by typing your question into the Causaly Discover search bar in natural language (Figure 4). “What is the incidence of NSCLC in patients with KRAS mutations?” will be used as an example (link).
Figure 4: Directly ask a question in natural language in the Causaly Discover search bar
The AI-generated summary and the relevant citations will be updated reflecting the rephrasing to the question.
Want to learn more about how to find evidence in Causaly?
Find more information and examples on how to search posts by clicking here.