How to search for disease comorbidities

This guide will take approximately 3 minutes to complete.

In this guide you will learn:

  • How to search for disease comorbidities in Causaly Discover 
  • How to refine your search to a specific context using filters 
  • How to refine your search using follow up questions 

Step 0: Login

Refer to https://med.causaly.com

TIP! In case you’ve forgotten your password, you can recover it here.

Step 1: Search for disease comorbidities 

To explore all comorbidities associated with a disease of interest, use Causaly Discover in the Causaly home page (Figure 1). 

Figure 1. Causaly Discover on the Causaly homepage 

Begin your search by typing your question into the Causaly Discover search bar in natural language (Figure 2). “What are the comorbidities of rheumatoid arthritis?” will be used as an example (link). 

Figure 2: Directly ask a question in natural language in the Causaly Discover search bar 

Click "Search" or hit Enter on your keyboard to run the search, which will direct you to the Causaly Discover results page.  

Causaly Discover offers an AI-generated summary, complete with in-line citations for transparency into the results, based on the top 20 articles. You can scroll down to view all the documents retrieved in response to your search query. 

In addition, Causaly Discover will prompt you to visit the Bio Graph to review the comorbidities in a dendrogram list and be able to deep dive into their unique relationships with the disease of interest. Click on View analysis to open the Causaly Bio Graph knowledge card (Figure 3). 

Figure 3: Causaly Bio Graph card linking your search query to Causaly dendrogram  results. 

 

TIP!  

  • To examine how Causaly retrieves the top 20 documents, please visit this guide.
  • If you are used to working with keywords on Intelligent Search and/or would like to review the results directly in the Causaly Biograph, you can select the option to return to your previous Causaly experience and initiate your search there by clicking the “Intelligent Search” option under “Biograph” on top of your Causaly homepage (Figure 4).

    Figure 4: The Intelligent Search option below the Biograph card 

    Before exploring the dendrogram list, you can explore how Causaly constructed the search. Click on the filter panel on the left represented by 3 horizontal lines. You will notice that Causaly has pre-selected some filters to answer your question.  

  • The Disorders category under the UMLS filter is preselected to refine the results to disorders. You can change the filters, based on what you consider as a comorbidity. 
  • To limit your results to the comorbidities associated with a specific organ system, for example the nervous system, select the category ‘Nervous system disorders’ under the MedDRA classification system in the filter panel on the left (Intelligent Search link) (Figure 5). The results will now display the nervous system disorders that are comorbidities of the disease of interest. 

    Figure 5: Refine results to “nervous system disorders” under the MedDRA classification system. 

Step 2: Refine your results with Causaly Copilot 

To further refine the results to a specific disorder, you can ask a follow-up question in Causaly Copilot. Remember Causaly Copilot is conversational so you don’t have to type your initial question again. In the below example, we are looking for comorbidities of rheumatoid arthritis in women by simply writing “In women” in the Causaly Copilot window on the right (Figure 6). The system will understand you are looking for comorbidities of the disease in the specified population. Causaly copilot will provide you with an updated AI-generated summary of your updated results.  

Figure 6: Explore comorbidities of rheumatoid arthritis in women  

You can continue to refine your results with filters or by asking additional follow-up questions in Causaly Copilot. 

Want to learn more about how to find evidence in Causaly?

Find more information and examples on how to search posts by clicking here