This guide will take approximately 3 minutes to complete.
In this guide you will learn:
- How to search for side effects in Causaly Discover
- How to further refine your search to a specific context using filters
Step 0: Login
Refer to https://med.causaly.com
TIP! In case you’ve forgotten your password, you can recover it here.
Search for side effects of a drug or therapeutic
To explore all side effects associated with a disease of interest, use Causaly Discover in the Causaly home page (Figure 1).
Figure 1. Causaly Discover on the Causaly homepage
Begin your search by typing your question into the Causaly Discover search bar in natural language (Figure 2). “What are the side effects of levetiracetam?” will be used as an example (link).
Figure 2: Directly ask a question in natural language in the Causaly Discover search bar
Click "Search" or hit Enter on your keyboard to run the search, which will direct you to the Causaly Discover results page.
Causaly Discover offers an AI-generated summary, complete with in-line citations for transparency into the results, based on the top 20 articles. You can scroll down to view all the documents retrieved in response to your search query.
In addition, Causaly Discover will prompt you to visit the Bio Graph to review the side effects in a dendrogram list and be able to deep dive into their unique relationships with the drug of interest. Click on View analysis to open the Causaly Bio Graph knowledge card (Figure 3). 
Figure 3: Causaly Bio Graph card linking your search query to Causaly dendrogram results.
TIP!
- To examine how Causaly retrieves the top 20 documents, please visit this guide.
- If you are used to working with keywords on Intelligent Search and/or would like to review the results directly in the Causaly Biograph, you can select the option to return to your previous Causaly experience and initiate your search there by clicking the “Intelligent Search” option under “Biograph” on top of your Causaly homepage (Figure 4).
Figure 4: The Intelligent Search option below the Biograph card
Before exploring the dendrogram list, you can explore how Causaly constructed the search. Click on the filter panel on the left represented by 3 horizontal lines. You will notice that Causaly has pre-selected some filters to answer your question.
Refine your results using filters
- The Disorders category under the UMLS filter and the MedDRA classification system are preselected to refine the results to disorders. You can change the filters, based on what you consider as a side effect.
- To limit your results to the adverse effects associated with a specific organ system, for example the nervous system, select the category ‘Nervous system disorders’ under the MedDRA classification system in the filter panel on the left (Intelligent Search link) (Figure 5). The results will now display the nervous system disorders that are induced by the drug of interest.
Figure 5: Refine results to “nervous system disorders” under the MedDRA classification system.
Refine your results with Causaly Copilot
To further refine the results to a specific disorder, you can ask a follow-up question in Causaly Copilot. Remember Causaly Copilot is conversational so you don’t have to type your initial question again. In the below example, we are looking for side effects of levetiracetam in epilepsy by simply writing “In Epilepsy” in the Causaly Copilot window on the right (Figure 6). The system will understand you are looking for side effects of the drug in the specified disease. Causaly copilot will provide you with an updated AI-generated summary of your updated results. 
Figure 6: Explore side effects of levetiracetam in epilepsy
You can continue to refine your results with filters or by asking additional follow-up questions in Causaly Copilot.
Want to learn more about how to find evidence in Causaly?
Find more information and examples on how to search posts by clicking here.