This guide will take approximately 5 minutes to complete.
In this guide you will learn:
- How to search for adverse events associated with a drug
- How to search for drug-drug interactions
Step 0: Log in
Refer to https://med.causaly.com
TIP! In case you’ve forgotten your password, you can recover it here.
A. Investigate the safety profile of a drug
To explore the AEs associated with a drug of interest, use Causaly Discover in the Causaly home page (Figure 1).
Figure 1: Causaly Discover on the Causaly homepage
Begin your search by typing your question in natural language in the Causaly Discover search bar (Figure 2). “What are the adverse events associated with Vedolizumab?’ will be used as an example (link).
Figure 2: Directly ask a question in natural language in the Causaly Discover search bar
Click "Search" or hit Enter on your keyboard to run the search, which will direct you to the Causaly Discover results page.
Causaly Discover offers an AI-generated summary, complete with in-line citations for transparency into the results, based on the top 20 articles (Figure 3). You can scroll down to view all the documents retrieved in response to your search query.
Figure 3: AI- generated summary by Causaly Discover
Apply filters to refine the results of your search, for example focus on publications from the last 5 years (Figure 4).
Figure 4: Filtering options to refine your search results
Once you apply filters, the AI-generated summary will be automatically updated to reflect your filter selections.
In addition, Causaly Discover will prompt you to visit the Bio Graph to review the AEs in a dendrogram list and be able to deep dive into the relationships of interest. Click on “View analysis” to open the Causaly Bio Graph knowledge card (Figure 5).
Figure 5: Click on the “View analysis” button to review all AEs associated with a drug of interest in Causaly’s Bio Graph
Option 2: How to search for drug-drug interactions
To investigate drug-drug interactions between two substances, type your question into Causaly Discover in natural language (Figure 6). “What are the drug interactions between aspirin and ace inhibitors?” will be used as an example (link)
Figure 6: Directly ask a question in natural language in the Causaly Discover search bar
Click "Search" or hit Enter on your keyboard to run the search, which will direct you to the Causaly Discover results page.
Causaly Discover offers an AI-generated summary, complete with in-line citations for transparency into the results, based on the top 20 articles (Figure 7). You can scroll down to view all the documents retrieved in response to your search query.
Figure 7: AI- generated summary by Causaly Discover
Option 3: Find the incidence rate of a drug-induced indication
Begin your search by typing your question into the Causaly Discover search bar in natural language (Figure 8). “What is the incidence of internal bleeding in patients taking ACE inhibitors?” will be used as an example (link).
Figure 8: Directly ask a question in natural language in the Causaly Discover search bar
Click "Search" or hit Enter on your keyboard to run the search, which will direct you to the Causaly Discover results page.
Causaly Discover offers an AI-generated summary, complete with in-line citations for transparency into the results, based on the top 20 articles (Figure 9). You can scroll down to view all the documents retrieved in response to your search query.
Figure 9: AI- generated summary by Causaly Discover
TIP! You can ask a follow-up question to refine this search for countries, geographical areas, age group or a specific metric.
Want to learn more about how to find evidence in Causaly?
Find more information and examples on how to search posts by clicking here.