This guide will take approximately 5 minutes to complete.
The purpose of this guide is to help you identify whether specific markers are used as surrogate molecular endpoints in disease Y.
Step 0: Login
Refer to https://med.causaly.com
TIP! In case you’ve forgotten your password, you can recover it here.
Step 1: Search for outcomes measured in disease X
To explore all outcomes associated with a disease of interest, use Causaly Discover in the Causaly home page (Figure 1).
Figure 1. Causaly Discover on the Causaly homepage
Begin your search by typing your question into the Causaly Discover search bar in natural language (Figure 2). “What are the clinical endpoints measured in diabetes?” will be used as an example (link).
Figure 2: Directly ask a question in natural language in the Causaly Discover search bar
Click "Search" or hit Enter on your keyboard to run the search, which will direct you to the Causaly Discover results page.
Causaly Discover offers an AI-generated summary, complete with in-line citations for transparency into the results, based on the top 20 articles. You can scroll down to view all the documents retrieved in response to your search query.
TIP! To refine the results based on your research objectives and/or quality standards, use the filters panel. Once you apply filters, the AI-generated summary will be automatically updated to reflect your filter selections.
Step 2: Find outcomes affected by a specific biomarker in a disease of interest
You can rephrase your question in the search bar or ask a follow-up question on the Copilot sidebar to identify which of clinical endpoints are associated with a biomarker of interest, such as Hba1c, in a disease context (Figure 3).
Figure 3: Type your follow up question in natural language in the Copilot side bar on the right
Results will now include publications that report clinical outcomes studied in Diabetes Mellitus patients in publications that report HbA1c.
Want to learn more about how to find evidence in Causaly?
Find more information and examples on how to search posts by clicking here.