This guide will take approximately 5 minutes to complete.
The purpose of this guide is to help you identify technologies and assays used to measure a biomarker of interest for patients with a specific indication, by:
- Exploring all procedures monitoring biomarker X in disease Y
- Performing a direct search between an investigative technique with biomarker X
Step 0: Login
Refer to https://med.causaly.com
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Search for procedures used to monitor biomarker X in disease Y
To explore all procedures associated with a biomarker of interest in a specific disease context, use Causaly Discover in the Causaly home page (Figure 1).
Figure 1. Causaly Discover on the Causaly homepage
Begin your search by typing your question into the Causaly Discover search bar in natural language (Figure 2). “What technologies are used to measure VEGFA in breast cancer?” will be used as an example (link).
Figure 2: Directly ask a question in natural language in the Causaly Discover search bar
Click "Search" or hit Enter on your keyboard to run the search, which will direct you to the Causaly Discover results page.
Causaly Discover offers an AI-generated summary, complete with in-line citations for transparency into the results, based on the top 20 articles. You can scroll down to view all the documents retrieved in response to your search query.
In addition, Causaly Discover will prompt you to visit the Bio Graph to review the assays in a dendrogram list and be able to deep dive into their unique relationships with the biomarker of interest. Click on the Causaly Bio Graph knowledge card to explore the comprehensive list of results (Figure 3). 
Figure 3: Causaly Bio Graph linking your search query to Causaly dendrogram results.
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- To examine how Causaly retrieves the top 20 documents, please visit this guide.
- If you are used to working with keywords on Bio Graph Search and/or would like to review the results directly in the Causaly Bio Graph, you can select the option to return to your previous Causaly experience and initiate your search there by clicking the “Bio Graph Search” option under “Bio Graph” on top of your Causaly homepage (Figure 4).
Figure 4: The Bio Graph Search option below the Bio Graph card
Before exploring the dendrogram list, you can explore how Causaly constructed the search. Click on the filter panel on the left represented by 3 horizontal lines. You will notice that Causaly has pre-selected some filters to answer your question.
Search for the direct relationship between a technology of interest used to measure biomarker X
To investigate whether a specific technique is used for the measurement of biomarker X, use Causaly Discover on the Causaly homepage.
Begin your search by typing your question into the Causaly Discover search bar in natural language. “Is Western blot used to measure VEGFA gene?” will be used as an example (link).
Similar to approach A, Causaly Discover will give you an AI-generated summary, complete with in-line citations for transparency into the results, based on the top 20 articles. You can scroll down to view all the documents retrieved in response to your search query.
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- You can further refine this search by using additional filters on the left of your screen. Filters include the publication type, year of publication, article section, data source, journal, and journal rank (SJR). To explore how you can best use the different filters, click here.
Want to learn more about how to find evidence in Causaly?
Find more information and examples on how to search posts by clicking here.